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Growth Hormone R

Growth Hormone R信息

英文名称:Growth hormone receptor上市药物数量28
中文名称生长激素受体临床药物数量29
靶点别称GHR,Somatotropin receptor,Serum-binding protein,GH-binding protein,GHBP,Growth Hormone Receptor,Growth Hormone Binding Protein,GH Receptor,Serum Binding Protein,GHIP,Receptors, Somatotropin最高研发阶段批准上市
英文名称:Growth hormone receptor
中文名称生长激素受体
靶点别称GHR,Somatotropin receptor,Serum-binding protein,GH-binding protein,GHBP,Growth Hormone Receptor,Growth Hormone Binding Protein,GH Receptor,Serum Binding Protein,GHIP,Receptors, Somatotropin
上市药物数量28
临床药物数量29
最高研发阶段Approved

Growth Hormone R产品列表

  • 属性

    Protein (9)

  • 产品库

    在线 (9)

  • 物种

    Human (4)Rhesus macaque (1)Canine (1)Rabbit (1)Rat (1)Cynomolgus (1)

  • 标签

    His Tag (6)Fc Tag (2)Fc Tag & Avi Tag (1)

  • 标记

    Biotin-labeled (2)Unconjugated (7)

共 9 项数据
  • 1

Growth Hormone R分子背景

Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormone-binding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin type-III domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

Growth Hormone R分子别名

GHR,GHBP,GH receptor

产品评论

  • wa********genscigroup.com 2024-11-21
    0人点赞
    我们购买了食蟹猴的GHR,用来免疫羊驼和骆驼,后面血清效价检测很不错,后续筛选也筛到不错的抗体,非常好用,蛋白活性比较好。
  • 25********qq.com 2024-07-29
    0人点赞
    这是一款我们经常使用的human GHR蛋白,有Fc标签,用起来很方便,动物免疫血清效价及活性验证结果都很不错,每次遇到问题技术服务态度特别温和,解决问题很迅速
  • ga*******126.com 2024-07-25
    0人点赞
    使用该抗原重组蛋白进行了一系列抗体活性验证,蛋白活性稳定,结合特异性强,数据可重复性好,不同批次间产品的质量极其稳定,很实用。
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