选择语言
免费注册
关注公众号

Frizzled-5

Frizzled-5信息

英文名称:Frizzled-5上市药物数量0
中文名称卷曲蛋白受体5临床药物数量1
靶点别称Frizzled Class Receptor 5，C2orf31，HFZ5，Frizzled 5， Seven Transmembrane Spanning Receptor，Frizzled Family Receptor 5，Fz-5，FzE5，Seven-Transmembrane Receptor Frizzled-5，Chromosome 2 Open Reading Frame 31，Frizzled (Drosophila) Homolog 5，HFz5最高研发阶段临床一期
英文名称:Frizzled-5
中文名称卷曲蛋白受体5
靶点别称Frizzled Class Receptor 5，C2orf31，HFZ5，Frizzled 5， Seven Transmembrane Spanning Receptor，Frizzled Family Receptor 5，Fz-5，FzE5，Seven-Transmembrane Receptor Frizzled-5，Chromosome 2 Open Reading Frame 31，Frizzled (Drosophila) Homolog 5，HFz5
上市药物数量0
临床药物数量1
最高研发阶段Phase 1 Clinical

Frizzled-5产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    Fc Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

Frizzled-5分子背景

Frizzled-5 (FZD5) is also known as FzE5, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the beta-catenin pathway. FZD5 interacts with GOPC.

Frizzled-5分子别名

FZD5,Frizzled-5,C2orf31,,Fz-5,hFz5,FzE5
  • 分子信息
  • 产品列表