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Frizzled-4

Frizzled-4信息

英文名称:Frizzled-4上市药物数量0
中文名称卷曲蛋白-4临床药物数量1
靶点别称hFz4，FzE4，CD344，Frizzled 4， Seven Transmembrane Spanning Receptor，Fz-4，Frizzled Family Receptor 4，EVR1，Frizzled (Drosophila) Homolog 4，Frizzled Homolog 4 (Drosophila)，Exudative Vitreoretinopathy 1，WNT Receptor Frizzled-4，Frizzled Homolog 4，CD344 Antigen，FZD4S，FEVR，GPCR，Fz4最高研发阶段临床三期
英文名称:Frizzled-4
中文名称卷曲蛋白-4
靶点别称hFz4，FzE4，CD344，Frizzled 4， Seven Transmembrane Spanning Receptor，Fz-4，Frizzled Family Receptor 4，EVR1，Frizzled (Drosophila) Homolog 4，Frizzled Homolog 4 (Drosophila)，Exudative Vitreoretinopathy 1，WNT Receptor Frizzled-4，Frizzled Homolog 4，CD344 Antigen，FZD4S，FEVR，GPCR，Fz4
上市药物数量0
临床药物数量1
最高研发阶段Phase 3 Clinical

Frizzled-4产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    Fc Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

Frizzled-4分子背景

Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).

Frizzled-4分子别名

FZD4,Frizzled-4,CD344,Fz-4,hFz4,FzE4
  • 分子信息
  • 产品列表