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Fc gamma RIV / CD16-2

Fc gamma RIV / CD16-2信息

英文名称:P-selectin glycoprotein ligand-1上市药物数量0
中文名称P选择素糖蛋白配体1临床药物数量4
靶点别称P-selectin glycoprotein ligand 1，PSGL-1，SELPLG，Selectin P Ligand，Cutaneous Lymphocyte-Associated Associated Antigen，CD162 Antigen，CD162，PSGL1，CLA最高研发阶段临床二期
英文名称:P-selectin glycoprotein ligand-1
中文名称P选择素糖蛋白配体1
靶点别称P-selectin glycoprotein ligand 1，PSGL-1，SELPLG，Selectin P Ligand，Cutaneous Lymphocyte-Associated Associated Antigen，CD162 Antigen，CD162，PSGL1，CLA
上市药物数量0
临床药物数量4
最高研发阶段Phase 2 Clinical

Fc gamma RIV / CD16-2产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Mouse (2)

  • 标签

    His Tag (1)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (1)Biotin-labeled (1)

共 2 项数据
  • 1

Fc gamma RIV / CD16-2分子背景

FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions

Fc gamma RIV / CD16-2分子别名

Fc gamma RIV,CD16-2,Fcgr4

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