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Fc epsilon RI alpha

Fc epsilon RI alpha信息

英文名称:IgE Fc receptor, alpha-subunit上市药物数量1
中文名称IgE-Fc片段受体α亚基临床药物数量0
靶点别称Fc Fragment Of IgE, High Affinity I, Receptor For; Alpha Polypeptide,FCE1A,IgE Fc receptor subunit alpha,Fc-epsilon RI-alpha,FCER1A,Fc Fragment Of IgE Receptor Ia,Fc Fragment Of IgE, High Affinity I, Receptor For,Alpha Polypeptide,Fc Epsilon Receptor Ia,FcERI,Immunoglobulin E Receptor, High-Affinity, Of Mast Cells, Alpha Polypeptide,High Affinity Immunoglobulin Epsilon Receptor Alpha-Subunit,High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha,Fc IgE Receptor, Alpha Polypeptide,Fc Epsilon RI Alpha-Chain,FCER1最高研发阶段批准上市
英文名称:IgE Fc receptor, alpha-subunit
中文名称IgE-Fc片段受体α亚基
靶点别称Fc Fragment Of IgE, High Affinity I, Receptor For; Alpha Polypeptide,FCE1A,IgE Fc receptor subunit alpha,Fc-epsilon RI-alpha,FCER1A,Fc Fragment Of IgE Receptor Ia,Fc Fragment Of IgE, High Affinity I, Receptor For,Alpha Polypeptide,Fc Epsilon Receptor Ia,FcERI,Immunoglobulin E Receptor, High-Affinity, Of Mast Cells, Alpha Polypeptide,High Affinity Immunoglobulin Epsilon Receptor Alpha-Subunit,High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha,Fc IgE Receptor, Alpha Polypeptide,Fc Epsilon RI Alpha-Chain,FCER1
上市药物数量1
临床药物数量0
最高研发阶段Approved

Fc epsilon RI alpha产品列表

  • 属性

    Protein (5)Kits (1)

  • 产品库

    在线 (6)

  • 物种

    Human (4)Cynomolgus (2)

  • 标签

    His Tag (2)Fc Tag (2)His Tag & Avi Tag (1)- (1)

  • 标记

    Unconjugated (4)Biotin-labeled (1) (1)

共 6 项数据
  • 1

Fc epsilon RI alpha分子背景

High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Ig-like (immunoglobulin-like) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.

Fc epsilon RI alpha分子别名

FCER1A,FCE1A,FcERI

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