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ErbB3

ErbB3信息

英文名称:Receptor tyrosine-protein kinase erbB-3上市药物数量2
中文名称受体酪氨酸蛋白激酶erbB-3临床药物数量26
靶点别称EC:2.7.10.1,FERLK,EC 2.7.10,Proto-oncogene-like protein c-ErbB-3,HER3,ERBB3,Erb-B2 Receptor Tyrosine Kinase 3,V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3,Tyrosine Kinase-Type Cell Surface Receptor HER3,Human Epidermal Growth Factor Receptor 3,Lethal Congenital Contracture Syndrome 2,Receptor Tyrosine-Protein Kinase ErbB-3,EC 2.7.10.1,P180-ErbB3,P45-SErbB3,P85-SErbB3,MDA-BF-1,C-ErbB-3,C-ErbB3,ErbB3-S,ErbB-3,LCCS2,Receptor, ErbB-3最高研发阶段批准上市
英文名称:Receptor tyrosine-protein kinase erbB-3
中文名称受体酪氨酸蛋白激酶erbB-3
靶点别称EC:2.7.10.1,FERLK,EC 2.7.10,Proto-oncogene-like protein c-ErbB-3,HER3,ERBB3,Erb-B2 Receptor Tyrosine Kinase 3,V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3,Tyrosine Kinase-Type Cell Surface Receptor HER3,Human Epidermal Growth Factor Receptor 3,Lethal Congenital Contracture Syndrome 2,Receptor Tyrosine-Protein Kinase ErbB-3,EC 2.7.10.1,P180-ErbB3,P45-SErbB3,P85-SErbB3,MDA-BF-1,C-ErbB-3,C-ErbB3,ErbB3-S,ErbB-3,LCCS2,Receptor, ErbB-3
上市药物数量2
临床药物数量26
最高研发阶段Approved

ErbB3产品列表

  • 属性

    Protein (7)Cell (1)

  • 产品库

    在线 (8)

  • 物种

    Human (7)Mouse (1)

  • 标签

    His Tag (3)Fc Tag (1)Strep Tag (1)Mouse IgG Fc Tag (1)His Tag & Avi Tag (1)- (1)

  • 标记

    Unconjugated (5)FITC Labeled (1)Biotin-labeled (1)- (1)

共 8 项数据
  • 1

ErbB3分子背景

ErbB3,also known as Her3 (human epidermal growth factor receptor 3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain. It therefore can bind the ligand but cannot mediate the intracellular signal transduction through protein phosphorylation. However, it does form heterodimers with ErbB2 or other EGFR members responsible for tyrosine phosphorylation to give a receptor complex and initiate the related pathway, which lead to cell proliferation or differentiation. Overexpression of this protein has been reported in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.

ErbB3分子别名

ERBB3,HER3,LCCS2,MDA-BF-1,MGC88033,c-erbB3,erbB3-S,p180-ErbB3,p45-sErbB3,p85-sErbB3

产品评论

  • 25********qq.com 2025-06-10
    0人点赞
    首次用到小鼠her3蛋白,物流速度超快,第二天就收到蛋白了,马上安排了活性检测,活性数据完全符合预期,后期主要用于抗体筛选及活性检测工作,期待能够获得更优秀的结果。
  • 25********qq.com 2025-05-21
    0人点赞
    之前都是自己表达her3蛋白进行实验,最近应甲方要求采购了ACRO的蛋白,首先进行了一系列活性检测,蛋白活性稳定,特异性也很强,拿到的EC50数据非常准确,性价比高,值得购买。
  • 18*********163.com 2025-04-15
    0人点赞
    此蛋白是由生物素标记后得到的蛋白,节省了自己生物素标记时间,提高实验效率,在Elisa实验中结果稳定,重复性好。
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