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ErbB3

ErbB3信息

英文名称:Receptor tyrosine-protein kinase erbB-3上市药物数量2
中文名称受体酪氨酸蛋白激酶erbB-3临床药物数量26
靶点别称EC:2.7.10.1,FERLK,EC 2.7.10,Proto-oncogene-like protein c-ErbB-3,HER3,ERBB3,Erb-B2 Receptor Tyrosine Kinase 3,V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3,Tyrosine Kinase-Type Cell Surface Receptor HER3,Human Epidermal Growth Factor Receptor 3,Lethal Congenital Contracture Syndrome 2,Receptor Tyrosine-Protein Kinase ErbB-3,EC 2.7.10.1,P180-ErbB3,P45-SErbB3,P85-SErbB3,MDA-BF-1,C-ErbB-3,C-ErbB3,ErbB3-S,ErbB-3,LCCS2,Receptor, ErbB-3最高研发阶段批准上市
英文名称:Receptor tyrosine-protein kinase erbB-3
中文名称受体酪氨酸蛋白激酶erbB-3
靶点别称EC:2.7.10.1,FERLK,EC 2.7.10,Proto-oncogene-like protein c-ErbB-3,HER3,ERBB3,Erb-B2 Receptor Tyrosine Kinase 3,V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3,Tyrosine Kinase-Type Cell Surface Receptor HER3,Human Epidermal Growth Factor Receptor 3,Lethal Congenital Contracture Syndrome 2,Receptor Tyrosine-Protein Kinase ErbB-3,EC 2.7.10.1,P180-ErbB3,P45-SErbB3,P85-SErbB3,MDA-BF-1,C-ErbB-3,C-ErbB3,ErbB3-S,ErbB-3,LCCS2,Receptor, ErbB-3
上市药物数量2
临床药物数量26
最高研发阶段Approved

ErbB3产品列表

  • 属性

    Protein (7)Cell (1)

  • 产品库

    在线 (8)

  • 物种

    Human (7)Mouse (1)

  • 标签

    His Tag (3)Fc Tag (1)Strep Tag (1)Mouse IgG Fc Tag (1)His Tag & Avi Tag (1)- (1)

  • 标记

    Unconjugated (5)FITC Labeled (1)Biotin-labeled (1)- (1)

共 8 项数据
  • 1

ErbB3分子背景

ErbB3,also known as Her3 (human epidermal growth factor receptor 3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain. It therefore can bind the ligand but cannot mediate the intracellular signal transduction through protein phosphorylation. However, it does form heterodimers with ErbB2 or other EGFR members responsible for tyrosine phosphorylation to give a receptor complex and initiate the related pathway, which lead to cell proliferation or differentiation. Overexpression of this protein has been reported in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.

ErbB3分子别名

ERBB3,HER3,LCCS2,MDA-BF-1,MGC88033,c-erbB3,erbB3-S,p180-ErbB3,p45-sErbB3,p85-sErbB3

产品评论

  • 21********qq.com 2025-06-30
    0人点赞
    之前用其他品牌的Mouse her3蛋白筛选纳米抗体库,由于蛋白活性不稳定,一直没有富集成功,最近换ACRO的重组蛋白重复筛选实验,筛选第三轮就明显富集了,真的太好用了。
  • 25********qq.com 2025-06-30
    0人点赞
    由于我们自己表达小鼠的her3蛋白质量一直都很差,而且浪费了很多时间。所以最近选择了ACRO的该货号蛋白,不仅拿到的数据可信度高,而且极快的推进了项目进度,价格也很实惠,太值了。
  • ru*******foxmail.com 2025-06-25
    0人点赞
    这个蛋白可好用了,我们公司这个平台一直采用这个公司的蛋白,检测抗原抗体的亲和力,结果与论文上十分吻合,后续我们也会进一步采用该公司的其他蛋白用于更多的检测平台。
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