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EpCAM

EpCAM信息

英文名称:Epithelial cell adhesion molecule上市药物数量1
中文名称上皮细胞粘附分子临床药物数量10
靶点别称Epithelial Cell Adhesion Molecule，Tumor-Associated Calcium Signal Transducer 1，Major Gastrointestinal Tumor-Associated Protein GA733-2，Cell Surface Glycoprotein Trop-1，Epithelial Glycoprotein 314，TROP1，KSA，Membrane Component， Chromosome 4， Surface Marker (35kD Glycoprotein)，Antigen Identified By Monoclonal Antibody AUA1，Human Epithelial Glycoprotein-2，Epithelial Cell Surface Antigen，CD326 Antigen，HEGP314，HNPCC8，Ep-CAM，DIAR5，EGP-2，EGP40，KS1/4，MK-1，M1S2，ESA，Ly74，TACST-1，CO-17A，17-1A，EGP34，HEA125，MH99，MOC31，323/A3，Trophoblast Cell Surface Antigen 1，Adenocarcinoma-associated antigen，EGP314，GA733-2，M4S1，TACSTD1，Epithelial glycoprotein，EGP，KS 1/4 antigen，MIC18，CD326，EPCAM最高研发阶段批准上市
英文名称:Epithelial cell adhesion molecule
中文名称上皮细胞粘附分子
靶点别称Epithelial Cell Adhesion Molecule，Tumor-Associated Calcium Signal Transducer 1，Major Gastrointestinal Tumor-Associated Protein GA733-2，Cell Surface Glycoprotein Trop-1，Epithelial Glycoprotein 314，TROP1，KSA，Membrane Component， Chromosome 4， Surface Marker (35kD Glycoprotein)，Antigen Identified By Monoclonal Antibody AUA1，Human Epithelial Glycoprotein-2，Epithelial Cell Surface Antigen，CD326 Antigen，HEGP314，HNPCC8，Ep-CAM，DIAR5，EGP-2，EGP40，KS1/4，MK-1，M1S2，ESA，Ly74，TACST-1，CO-17A，17-1A，EGP34，HEA125，MH99，MOC31，323/A3，Trophoblast Cell Surface Antigen 1，Adenocarcinoma-associated antigen，EGP314，GA733-2，M4S1，TACSTD1，Epithelial glycoprotein，EGP，KS 1/4 antigen，MIC18，CD326，EPCAM
上市药物数量1
临床药物数量10
最高研发阶段Approved

EpCAM产品列表

  • 属性

    Protein (12)Antibody (1)Cell (1)

  • 产品库

    在线 (14)

  • 物种

    Human (10)Mouse (1)Rhesus macaque (2)Rabbit (1)

  • 标签

    His Tag (4)Fc Tag (2)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Llama IgG Fc Tag (1)- (2)Tag Free (1)

  • 标记

    Unconjugated (8)Biotin-labeled (3)FITC Labeled (2)- (1)

共 14 项数据
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EpCAM分子背景

EpCAM is also known as CO171A, EGP, EGP40,GA7332, KSA, M4S, MIC18, MK1, TROP1, hEGP2, and is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas as 17-1A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (Ep-CAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy. Ep-CAM cross signaling with N-cadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (Ep-CAM) recently received increased attention as a prognostic factor in breast cancer.

EpCAM分子别名

EPCAM,TACSTD1,TROP1,CD326,DIAR5,EGP2,EGP314,EGP40,ESA,GA733-2,HNPCC8,HNPCC-8,KS1,4,KSA,M4S1,MIC18,MK1

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产品评论

  • 2025-09-10
    0人点赞
    FITC-Labeled Human EpCAM / TROP1 Protein, Fc Tag
    这款产品效果非常好，能非常灵敏、快捷的检测目标CAR的表达。完美解决了CAR-T构建过程中遇到的抗原表位被遮蔽的问题，强烈推荐！！野生型细胞与CAR-细胞背景很低，1ug，3ug，10ug/ml 该产品使用浓度，结果无明显差异。
  • 1qq.com 2025-07-31
    0人点赞
    FITC-Labeled Human EpCAM / TROP1 Protein, His Tag
    我测试了FITC-EpCAM蛋白与我们的抗EpCAM CAR-T细胞的结合情况，这些CAR-T细胞是通过人类T细胞的慢病毒转导制成的。在10 ug/ml和 2 ug/ml的浓度下，该蛋白染色了CAR-T细胞，但没有染色对照T细胞。总体而言这是一个很好的产品。
  • 21********qq.com 2025-05-27
    2人点赞
    Human EpCAM / TROP1 Protein, His Tag
    :我们使用的trop1和trop2蛋白都选择的是百普赛斯的，效果都很不错，不仅活性稳定，特异性强，而且批间差异也很小，性价比高，对于科研工作而言，选择百普赛斯的蛋白不愧是最佳选择。
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