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ENPP-2

ENPP-2信息

英文名称:Ectonucleotide pyrophosphatase/phosphodiesterase 2上市药物数量0
中文名称核苷酸内焦磷酸酶/磷酸二酯酶2临床药物数量9
靶点别称EC:3.1.4.39，ATX，Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 2，Phosphodiesterase I/Nucleotide Pyrophosphatase 2，Plasma Lysophospholipase D，Autotaxin-T，EC 3.1.4.39，PD-IALPHA，ATX-X，NPP2，E-NPP 2，Autotaxin，ENPP2，PDNP2，Ectonucleotide Pyrophosphatase/Phosphodiesterase 2，Extracellular Lysophospholipase D，LysoPLD最高研发阶段临床二期
英文名称:Ectonucleotide pyrophosphatase/phosphodiesterase 2
中文名称核苷酸内焦磷酸酶/磷酸二酯酶2
靶点别称EC:3.1.4.39，ATX，Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 2，Phosphodiesterase I/Nucleotide Pyrophosphatase 2，Plasma Lysophospholipase D，Autotaxin-T，EC 3.1.4.39，PD-IALPHA，ATX-X，NPP2，E-NPP 2，Autotaxin，ENPP2，PDNP2，Ectonucleotide Pyrophosphatase/Phosphodiesterase 2，Extracellular Lysophospholipase D，LysoPLD
上市药物数量0
临床药物数量9
最高研发阶段Phase 2 Clinical

ENPP-2产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    His Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

ENPP-2分子背景

Autotaxin also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (E-NPP 2 or ENPP2), Extracellular lysophospholipase D (LysoPLD), Autotaxin (ATX or ATX-X), which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP2 contains two SMB (somatomedin-B) domains. ENPP2 hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. ENPP2 can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. ENPP2 stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein.

ENPP-2分子别名

ENPP-2,E-NPP 2,Autotaxin,LysoPLD,ATX,PDNP2,ATX-X,NPP2,PD-IALPHA

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