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DNAM-1

DNAM-1信息

英文名称:CD226 antigen上市药物数量0
中文名称临床药物数量0
靶点别称DNAX accessory molecule 1，DNAM-1，T Lineage-Specific Activation Antigen 1 Antigen，PTA1，DNAX Accessory Molecule-1，Adhesion Glycoprotein，TLiSA1，DNAM1，CD226 Molecule，Platelet And T Cell Activation Antigen 1最高研发阶段临床前
英文名称:CD226 antigen
中文名称
靶点别称DNAX accessory molecule 1，DNAM-1，T Lineage-Specific Activation Antigen 1 Antigen，PTA1，DNAX Accessory Molecule-1，Adhesion Glycoprotein，TLiSA1，DNAM1，CD226 Molecule，Platelet And T Cell Activation Antigen 1
上市药物数量0
临床药物数量0
最高研发阶段Preclinical

DNAM-1产品列表

  • 属性

    Protein (5)

  • 产品库

    在线 (5)

  • 物种

    Human (3)Cynomolgus (1)Mouse (1)

  • 标签

    His Tag (3)Fc Tag (1)Fc Tag & Avi Tag (1)

  • 标记

    Unconjugated (4)Biotin-labeled (1)

共 5 项数据
  • 1

DNAM-1分子背景

DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

DNAM-1分子别名

DNAM1,CD226,PTA1
  • 产品列表