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Coagulation factor XI

Coagulation factor XI信息

英文名称:Coagulation factor XI上市药物数量2
中文名称凝血因子XI临床药物数量27
靶点别称EC 3.4.21，EC:3.4.21.27，FXI，F11，PTA，Coagulation Factor XI，Plasma Thromboplastin Antecedent，EC 3.4.21.27，Factor XI，Coagualtion Factor XI最高研发阶段批准上市
英文名称:Coagulation factor XI
中文名称凝血因子XI
靶点别称EC 3.4.21，EC:3.4.21.27，FXI，F11，PTA，Coagulation Factor XI，Plasma Thromboplastin Antecedent，EC 3.4.21.27，Factor XI，Coagualtion Factor XI
上市药物数量2
临床药物数量27
最高研发阶段Approved

Coagulation factor XI产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Human (1)Rhesus macaque (1)

  • 标签

    His Tag (2)

  • 标记

    Unconjugated (2)

共 2 项数据
  • 1

Coagulation factor XI分子背景

This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality

Coagulation factor XI分子别名

Coagulation factor XI,FXI,PTA,F11
  • 分子信息
  • 产品列表