选择语言
免费注册
关注公众号
微信客服

Claudin-18.2

Claudin-18.2信息

英文名称:Claudin-18 splice variant 2上市药物数量1
中文名称密蛋白-18剪接变体2临床药物数量74
靶点别称UNQ778/PRO1572，CLDN18，Claudin 18，Surfactant Associated Protein J，Surfactant， Pulmonary Associated Protein J，Surfactant Associated 5，Claudin-18，SFTA5，SFTPJ，Claudin 18.2，CLDN18.2最高研发阶段临床三期
英文名称:Claudin-18 splice variant 2
中文名称密蛋白-18剪接变体2
靶点别称UNQ778/PRO1572，CLDN18，Claudin 18，Surfactant Associated Protein J，Surfactant， Pulmonary Associated Protein J，Surfactant Associated 5，Claudin-18，SFTA5，SFTPJ，Claudin 18.2，CLDN18.2
上市药物数量1
临床药物数量74
最高研发阶段Phase 3 Clinical

Claudin-18.2产品列表

  • 属性

    Cell (1)Protein (11)Antibody (1)Kits (1)

  • 产品库

    在线 (14)

  • 物种

    Human (8)Human / Cynomolgus (2)Mouse (4)

  • 标签

    - (10)His Tag & Strep Tag (3)GFP Tag (1)

  • 标记

    - (2)Unconjugated (7)GFP Fusion (1)Biotin-labeled (3)PE Labeled (1)

共 14 项数据
  • 1
  • 2

Claudin-18.2分子背景

Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on short-lived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells.

Claudin-18.2分子别名

Claudin-18.2,CLDN18,Claudin-18

抗体项目交易平台

Licensing 项目合作

产品评论

  • ch****kelun.com 2026-01-20
    0人点赞
    Human / Cynomolgus Claudin-18.2 Protein, His,Twin-Strep Tag (Detergent)
    购买该蛋白用于分子互作验证：特异性结合人/食蟹猴Claudin-18.2靶向抗体，量化抗体亲和力，明确药物的跨物种结合能力，支撑临床前食蟹猴药效实验，产品很可靠
  • 85*******qq.com 2026-01-15
    0人点赞
    Biotinylated Human Claudin-18.2 Protein, His,Avitag™&Flag Tag (Detergent)
    最近在优化SA芯片，大批量筛选SA原料。正好有ACRO的生物素标记的Claudin-18.2 Protein，可以多方面验证芯片性能。实验梯度明显，响应值正常，说明ACRO的蛋白质量好，也证明我们筛选的原料可正常使用
  • tm*****sina.cn 2025-11-24
    1人点赞
    Biotinylated Human Claudin-18.2 Protein, His,Avitag™&Flag Tag (Detergent)
    这个claudin18.2是很经典的膜蛋白，一般来说纯化是比较困难的。Acro家对于一些膜蛋白的生产质量还是很稳定的，能够模拟蛋白的天然状态和结构。节省了我们大量的蛋白表达和纯化的摸索环节。我们拿这个biotin标记的蛋白进行竞争性ELISA实验，来鉴别不同抗体的结合特性。Acro的biotin标记活性很高，而且纯度不错，保证了实验的稳定性和均一性。
加载更多
  • 分子信息
  • 产品列表