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CD206

CD206信息

英文名称:Macrophage mannose receptor 1上市药物数量1
中文名称巨噬细胞甘露糖受体-1临床药物数量0
靶点别称C-type lectin domain family 13 member D，CLEC13D，Macrophage mannose receptor 1-like protein 1，hMR，Macrophage mannose receptor 1，C-type lectin domain family 13 member D-like，CLEC13DL，MRC1L1，MRC1，Mannose Receptor C-Type 1，Mannose Receptor， C Type 1-Like 1，Human Mannose Receptor，MMR，Mannose Receptor， C Type 1，CD206 Antigen，BA541I19.1，CD206最高研发阶段批准上市
英文名称:Macrophage mannose receptor 1
中文名称巨噬细胞甘露糖受体-1
靶点别称C-type lectin domain family 13 member D，CLEC13D，Macrophage mannose receptor 1-like protein 1，hMR，Macrophage mannose receptor 1，C-type lectin domain family 13 member D-like，CLEC13DL，MRC1L1，MRC1，Mannose Receptor C-Type 1，Mannose Receptor， C Type 1-Like 1，Human Mannose Receptor，MMR，Mannose Receptor， C Type 1，CD206 Antigen，BA541I19.1，CD206
上市药物数量1
临床药物数量0
最高研发阶段Approved

CD206产品列表

  • 属性

    Protein (6)

  • 产品库

    在线 (6)

  • 物种

    Human (3)Mouse (2)Cynomolgus (1)

  • 标签

    His Tag (4)His Tag & Avi Tag (2)

  • 标记

    Unconjugated (3)Biotin-labeled (3)

共 6 项数据
  • 1

CD206分子背景

Mrc1 is a conserved checkpoint mediator protein that transduces the replication stress signal to the downstream effector kinase. Mrc1 and its vertebrate homologue Claspin serve as a mediator for replication stress checkpoint signaling, receiving the signal from Mec1/Rad3/ATR sensor kinase and transmitting it to the effector Rad53/Cds1/Chk1 kinase. The loss of mrc1 checkpoint activity results in the aberrant activation of late/dormant origins in the presence of hydroxyurea. Tumor-associated macrophages (TAMs) expressing the multi-ligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immunosuppression, angiogenesis, metastasis, and relapse.

CD206分子别名

MMR,CD206,hMR,MRC1,CLEC13D,CLEC13DL,MRC1L1
  • 分子信息
  • 产品列表