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CD109

CD109信息

英文名称:DNA polymerase alpha subunit上市药物数量2
中文名称DNA聚合酶α亚基临床药物数量3
靶点别称P180，N Syndrome (Mental Retardation， Malformations， Chromosome Breakage)，NSX，VEODS，Polymerase (DNA Directed)， Alpha，POLA1，Polymerase (DNA-Directed)， Alpha (70kD)，DNA Polymerase Alpha 1， Catalytic Subunit，POLA，EC:2.7.7.7，EC 2.7.7.7，DNA Polymerase Alpha Catalytic Subunit，DNA Polymerase Alpha Catalytic Subunit P180，Polymerase (DNA) Alpha 1， Catalytic Subunit，DNA Polymerase I，Polymerase (DNA Directed)， Alpha 1， Catalytic Subunit最高研发阶段批准上市
英文名称:DNA polymerase alpha subunit
中文名称DNA聚合酶α亚基
靶点别称P180，N Syndrome (Mental Retardation， Malformations， Chromosome Breakage)，NSX，VEODS，Polymerase (DNA Directed)， Alpha，POLA1，Polymerase (DNA-Directed)， Alpha (70kD)，DNA Polymerase Alpha 1， Catalytic Subunit，POLA，EC:2.7.7.7，EC 2.7.7.7，DNA Polymerase Alpha Catalytic Subunit，DNA Polymerase Alpha Catalytic Subunit P180，Polymerase (DNA) Alpha 1， Catalytic Subunit，DNA Polymerase I，Polymerase (DNA Directed)， Alpha 1， Catalytic Subunit
上市药物数量2
临床药物数量3
最高研发阶段Approved

CD109产品列表

  • 属性

    Protein (4)

  • 产品库

    在线 (4)

  • 物种

    Human (3)Cynomolgus (1)

  • 标签

    His Tag & Avi Tag (1)Fc Tag (1)His Tag (2)

  • 标记

    Biotin-labeled (1)Unconjugated (3)

共 4 项数据
  • 1

CD109分子背景

CD109 is a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. CD109 is expressed in many malignant tumors, including various squamous cell carcinomas and adenocarcinomas, and plays a role as a multifunctional coreceptor.CD109 reportedly associates with transforming growth factor (TGF)-β receptors and negatively regulates TGF-β signaling in keratinocytes. Additionally, CD109 is potentially related to signal transducer and activator of transcription-3 signaling and aberrant cell proliferation.

CD109分子别名

CD109,CPAMD7,r150,p180,CPAMD7
  • 分子信息
  • 产品列表