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BCMA

BCMA信息

英文名称:B-cell maturation protein上市药物数量7
中文名称B细胞成熟蛋白临床药物数量120
靶点别称B-Cell Maturation Protein，B-Cell Maturation Factor，B Cell Maturation Antigen，CD269 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 17，TNFRSF17，TNFRSF13A，CD269，BCM，BCMA，TNF Receptor Superfamily Member 17，Tumor Necrosis Factor Receptor Superfamily， Member 17，B-Cell Maturation Antigen最高研发阶段临床三期
英文名称:B-cell maturation protein
中文名称B细胞成熟蛋白
靶点别称B-Cell Maturation Protein，B-Cell Maturation Factor，B Cell Maturation Antigen，CD269 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 17，TNFRSF17，TNFRSF13A，CD269，BCM，BCMA，TNF Receptor Superfamily Member 17，Tumor Necrosis Factor Receptor Superfamily， Member 17，B-Cell Maturation Antigen
上市药物数量7
临床药物数量120
最高研发阶段Phase 3 Clinical

BCMA产品列表

  • 属性

    Protein (27)Antibody (1)Beads (1)Cell Grade Beads (1)Kits (1)Cell (1)

  • 产品库

    在线 (34)

  • 物种

    Human (20)Cynomolgus / Rhesus macaque (5)Mouse (4)Canine (1)Rabbit (1)Rat (1)

  • 标签

    Fc Tag (4)His Tag (15)Fc Tag & Avi Tag (3)Llama IgG Fc Tag (2)His Tag & Avi Tag (3)Mouse IgG Fc Tag (1)Mouse IgG1 (1)- (5)

  • 标记

    Unconjugated (13)FITC Labeled (3)Biotin-labeled (6) (1)PE Labeled (2)APC Labeled (2)AF488 Labeled (1)AF647 Labeled (1)AF555 Labeled (1)- (4)

共 32 项数据
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BCMA分子背景

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

BCMA分子别名

TNFRSF17,CD269,BCM,BCMA

抗体项目交易平台

Licensing 项目合作

产品评论

  • 22********qq.com 2025-05-27
    0人点赞
    Mouse BCMA / TNFRSF17 Protein, His Tag
    购买Mouse BCMA蛋白主要用于筛选具有人鼠交叉结合活性的候选抗体分子。先用human BCMA蛋白进行了固相筛选，成功富集后换Mouse BCMA继续筛选依然富集成功，通过ELISA活性检测成功获得多个具有交叉活性的抗体蛋白。实验很顺利，蛋白都是ACRO的，值得推荐。
  • ch*******genscriptprobio.com 2025-03-23
    0人点赞
    Biotinylated Human BCMA / TNFRSF17 Protein, His,Avitag™, premium grade
    用了ACRO家的biotinlated human BCMA 抗原，进行了亲和力成熟抗体筛选，通过ELISA和SPR，筛选到了亲和力相比parental WT提升100倍的突变克隆。抗原性质稳定，批次间没有差异，助力项目获得非常好的分子。
  • ch*******genscriptprobio.com 2025-03-23
    0人点赞
    Mouse BCMA / TNFRSF17 Protein, His Tag
    用了ACRO家的mouse,cyno,human BCMA 抗原，进行了抗体工程改造和亲和力成熟抗体筛选，通过ELISA和SPR，筛选到了亲和力相比parental WT提升100倍以上的克隆，同时满足亲和力提升和不同种属交叉。抗原性质稳定。
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