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Bcl-x

Bcl-x信息

英文名称:Apoptosis regulator Bcl-X上市药物数量2
中文名称Bcl-X蛋白临床药物数量7
靶点别称Bcl-2-like protein 1，Bcl2-L-1，BCL2L，Apoptosis regulator Bcl-X，BCL2L1，BCL2 Like 1，Protein Phosphatase 1， Regulatory Subunit 52，BCLX，BCL-XL/S，PPP1R52，Bcl-X，bcl-X Protein，Bcl-XL，Bcl-XS最高研发阶段批准上市
英文名称:Apoptosis regulator Bcl-X
中文名称Bcl-X蛋白
靶点别称Bcl-2-like protein 1，Bcl2-L-1，BCL2L，Apoptosis regulator Bcl-X，BCL2L1，BCL2 Like 1，Protein Phosphatase 1， Regulatory Subunit 52，BCLX，BCL-XL/S，PPP1R52，Bcl-X，bcl-X Protein，Bcl-XL，Bcl-XS
上市药物数量2
临床药物数量7
最高研发阶段Approved

Bcl-x产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Human (2)

  • 标签

    His Tag (1)GST Tag (1)

  • 标记

    Unconjugated (2)

共 2 项数据
  • 1

Bcl-x分子背景

Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.

Bcl-x分子别名

BCL2L1,Bcl-XL,Bcl2-L-1,BCL-XL,S,BCL2L,BCLX,BCLXL,BCLXS,Bcl-X,bcl-xS
  • 分子信息
  • 产品列表