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BAFFR

BAFFR信息

英文名称:B-cell activating factor receptor上市药物数量0
中文名称B细胞活化因子受体临床药物数量8
靶点别称BAFFR，B Cell-Activating Factor Receptor，Prolixin，BROMIX，CD268，Tumor Necrosis Factor Receptor Superfamily， Member 13C，Tumor Necrosis Factor Receptor Superfamily Member 13C，BR3，CVID4，CD268 Antigen，BAFF Receptor，B-Cell Activation Factor Receptor，BAFF-R，TNF Receptor Superfamily Member 13C，BLyS Receptor 3，B-Cell-Activating Factor Receptor，TNFRSF13C最高研发阶段临床三期
英文名称:B-cell activating factor receptor
中文名称B细胞活化因子受体
靶点别称BAFFR，B Cell-Activating Factor Receptor，Prolixin，BROMIX，CD268，Tumor Necrosis Factor Receptor Superfamily， Member 13C，Tumor Necrosis Factor Receptor Superfamily Member 13C，BR3，CVID4，CD268 Antigen，BAFF Receptor，B-Cell Activation Factor Receptor，BAFF-R，TNF Receptor Superfamily Member 13C，BLyS Receptor 3，B-Cell-Activating Factor Receptor，TNFRSF13C
上市药物数量0
临床药物数量8
最高研发阶段Phase 3 Clinical

BAFFR产品列表

  • 属性

    Protein (11)

  • 产品库

    在线 (13)

  • 物种

    Mouse (3)Human (6)Cynomolgus (1)Rat (1)

  • 标签

    Fc Tag & Avi Tag (2)Fc Tag (2)Llama IgG Fc Tag (1)His Tag (5)His Tag & Avi Tag (1)

  • 标记

    Biotin-labeled (3)Unconjugated (7)PE Labeled (1)

共 11 项数据
  • 1
  • 2

BAFFR分子背景

BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

BAFFR分子别名

BAFFR,TNFRSF13C,BROMIX,CD268,CVID4,prolixin,BAFF-R

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产品评论

  • tm*****sina.cn 2024-09-06
    0人点赞
    Mouse BAFFR / TNFRSF13C Protein, His Tag (HPLC verified)
    该小鼠蛋白表达与B细胞的表面，我们购买该蛋白是用于相关的小鼠体内结合实验。数据显示该蛋白稳定可靠，能够优效的用于结合，功能抑制相关的实验。
  • tm*****sina.cn 2024-09-06
    0人点赞
    Cynomolgus BAFFR / TNFRSF13C Protein, His Tag (MALS verified)
    最近随着血液瘤和免疫疾病的热潮，该TNFRSF13C蛋白可以很好的帮助建立体外筛选平台，能够快速的进行体外结合筛选实验。对于B细胞相关的实验也是可以使用的。
  • zh***chempartner.com 2024-04-17
    0人点赞
    Mouse BAFFR / TNFRSF13C Protein, His Tag (HPLC verified)
    我们购买该产品用于SPR亲和力测定，该产品质量一如既往较好，包装也严实，冻干粉压的比较实，飞粉少。实验结果也比较符合我们的期待值，产品说明较为详细。
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