B7-H4

B7-H4信息

英文名称:V-set domain-containing T-cell activation inhibitor 1上市药物数量0
中文名称含V区域T细胞激活抑制因子1临床药物数量10
靶点别称V-Set Domain-Containing T-Cell Activation Inhibitor 1,Immune costimulatory protein B7-H4,B7h.5,B7 homolog 4,T-cell costimulatory molecule B7x,V-Set Domain Containing T Cell Activation Inhibitor 1,B7X,B7 Family Member, H4,T Cell Costimulatory Molecule B7x,B7S1,B7 Superfamily Member 1,VCTN1,PRO1291,FLJ22418,B7H4,B7-H4,Protein B7S1最高研发阶段临床三期
英文名称:V-set domain-containing T-cell activation inhibitor 1
中文名称含V区域T细胞激活抑制因子1
靶点别称V-Set Domain-Containing T-Cell Activation Inhibitor 1,Immune costimulatory protein B7-H4,B7h.5,B7 homolog 4,T-cell costimulatory molecule B7x,V-Set Domain Containing T Cell Activation Inhibitor 1,B7X,B7 Family Member, H4,T Cell Costimulatory Molecule B7x,B7S1,B7 Superfamily Member 1,VCTN1,PRO1291,FLJ22418,B7H4,B7-H4,Protein B7S1
上市药物数量0
临床药物数量10
最高研发阶段Phase 3 Clinical

B7-H4产品列表

  • 属性

    Protein (10)Cell (1)

  • 产品库

    在线 (11)

  • 物种

    Human (5)Mouse (2)Cynomolgus / Rhesus macaque (2)Rat (1)Canine (1)

  • 标签

    His Tag (7)His Tag & Avi Tag (2)Fc Tag (1)- (1)

  • 标记

    Biotin-labeled (3)Unconjugated (6)Azide Labeled (1)- (1)

共 11 项数据
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B7-H4分子背景

V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.

B7-H4分子别名

B7-H4,VTCN1,B7S1,B7h.5

产品评论

  • 2026-02-02
    0人点赞
    此B7-H4蛋白运输迅速,包装精美,纯度高,稳定性好,Elisa实验结果稳定,重复性好,质量和性价比高,实验结果符合预期。
  • 13*********163.com 2026-02-02
    2人点赞
    我们购买这个B7H4蛋白用来做抗体筛选工作,这个抗原参与了抗体的选择与验证全流程。通过这个多维验证的高质量抗体,显著提升了科研数据可靠性。
  • su**********163.com 2025-07-13
    5人点赞
    使用这个蛋白包被ELISA板子,样本检测的是大鼠二免14天免疫10μg低剂量的血清,血清是从20万开始稀释,随后2倍比稀释至第8个孔,这个图是检测得到OD值数据结果,标黄孔的对应稀释倍数是样本的抗体滴度。
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