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Angiogenin

Angiogenin信息

英文名称:Cleavage and polyadenylation specificity factor subunit 3上市药物数量0
中文名称切割和聚腺苷酸特异性因子3临床药物数量2
靶点别称YSH1，Cleavage And Polyadenylation Specificity Factor 73 KDa Subunit，Cleavage And Polyadenylation Specific Factor 3， 73kD Subunit，CPSF 73 KDa Subunit，NEDMHSN，NEDMHS，EC 3.1.27，Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit)，mRNA 3'-end-processing endonuclease CPSF-73，CPSF73，Cleavage And Polyadenylation Specific Factor 3，CPSF-73，Cleavage And Polyadenylation Specificity Factor Subunit 3，Cleavage And Polyadenylation Specific Factor 3， 73kDa，MRNA 3'-End-Processing Endonuclease CPSF-73最高研发阶段临床一期
英文名称:Cleavage and polyadenylation specificity factor subunit 3
中文名称切割和聚腺苷酸特异性因子3
靶点别称YSH1，Cleavage And Polyadenylation Specificity Factor 73 KDa Subunit，Cleavage And Polyadenylation Specific Factor 3， 73kD Subunit，CPSF 73 KDa Subunit，NEDMHSN，NEDMHS，EC 3.1.27，Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit)，mRNA 3'-end-processing endonuclease CPSF-73，CPSF73，Cleavage And Polyadenylation Specific Factor 3，CPSF-73，Cleavage And Polyadenylation Specificity Factor Subunit 3，Cleavage And Polyadenylation Specific Factor 3， 73kDa，MRNA 3'-End-Processing Endonuclease CPSF-73
上市药物数量0
临床药物数量2
最高研发阶段Phase 1 Clinical

Angiogenin产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    His Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

Angiogenin分子背景

Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo

Angiogenin分子别名

ALS9,ANG,Angiogenin,angiogenin, ribonuclease, RNase A family, 5,EC 3.1.27,EC:3.1.27.-
  • 分子信息
  • 产品列表