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Human LILRB5 / CD85c / LIR-8 Protein, His Tag

分子别名(Synonym)

LILRB5,CD85c,LIR-8

表达区间及表达系统(Source)

Human LILRB5, His Tag (CDC-H5220) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Gly 458 (Accession # NP_006831).

Predicted N-terminus: Gly 24

蛋白结构(Molecular Characterization)

Online(Gly 24 - Gly 458) NP_006831

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 49.2 kDa. The protein migrates as 66-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human LILRB5, His Tag (Cat. No. CDC-H5220) SDS-PAGE gel

Human LILRB5, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

背景(Background)

Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5), also known as CD85c and LIR-8, belongs to the leukocyte immunoglobulin-like receptor (LIR) family of transmembrane glycoproteins that negatively regulate immune cell activation. Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response.

 

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