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 >  Protein>OX40 >OX0-R5254

Rabbit OX40 / TNFRSF4 / CD134 Protein, Fc Tag

分子别名(Synonym)

TNFRSF4,OX40,CD134,OX40L receptor,ACT35,TXGP1L

表达区间及表达系统(Source)

Rabbit OX40, Fc Tag (OX0-R5254) is expressed from human 293 cells (HEK293). It contains AA Ala 19 - Gln 208 (Accession # O02764).

Predicted N-terminus: Ala 19

Request for sequence

蛋白结构(Molecular Characterization)

Online(Ala 19 - Gln 208) O02764

This protein carries a human IgG1 Fc tag at the C-terminus.

The protein has a calculated MW of 47.3 kDa. As a result of different glycosylation, the protein migrates as 48 kDa and 68 kDa under reducing (R) condition, and 120-135 kDa under non-reducing (NR) condition (SDS-PAGE).

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>85% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Rabbit OX40, Fc Tag (Cat. No. OX0-R5254) SDS-PAGE gel

Rabbit OX40, Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 85%.

背景(Background)

Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.

 

 

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OX40靶点信息
英文全称:Tumor necrosis factor receptor superfamily member 4
中文全称:肿瘤坏死因子受体超家族成员4
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:27详情
最高研发阶段:临床三期
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