PE-labeled Human CD47-coupled Magnetic Beads

背景（Background）

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

应用说明（Application）

This product is labeled by PE and coupled by CD47 protein in advance, no need to use fluorescent labeled secondary antibody, easy to flow cytometry.

重构方法（Reconstitution）

See Certificate of Analysis (CoA) for detailed instruction.

存储（Storage）

Upon receipt, please store the Beads at -20℃. The shelf life is 1 year at -20 ℃.

Please avoid more than 3 freeze-thaw cycles once reconstitution, immediate use after reconstitution is highly recommended.

制剂（Formulation）

Please contact us for detailed information.

Contact us for customized product form or formulation.