膜杰作
Star Staining
分子别名（Synonym）
Integrin alpha 8 beta 1,ITGA8&ITGB1
表达区间及表达系统（Source）
Rat ITGA8 & ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R53W6) is expressed from CHO cells. It contains AA Phe 38 - Pro 1034 (ITGA8) & Gln 21 - Asp 729 (ITGB1) (Accession # F7F1E3 (ITGA8) & P49134 (ITGB1)).
Predicted N-terminus: Phe 38 (ITGA8) & Gln 21 (ITGB1)
Request for sequence
蛋白结构（Molecular Characterization）
Rat ITGA8 & ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA8 and ITGB1, has a calculated MW of 117.2 kDa (ITGA8) and 83.7 kDa (ITGB1). The protein migrates as 50-55 kDa and 65-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
内毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
纯度（Purity）
>80% as determined by SDS-PAGE.
制剂（Formulation）
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
电泳（SDS-PAGE）
Rat ITGA8 & ITGB1 Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under non-reducing (NR) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 80% (With Star Ribbon Pre-stained Protein Marker).
背景（Background）
Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1. The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1. The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development. In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.
