Monoclonal Anti-Monkeypox-A29L Antibody, Mouse IgG1 (8E8) antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with A29L.
Mouse IgG1 | Mouse Kappa
This product is a specific antibody specifically reacts with A29L.
>95% as determined by SDS-PAGE.
Less than 1.0 EU per mg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS,pH 7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
Monoclonal Anti-Monkeypox-A29L Antibody, Mouse IgG1 (8E8) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Monkeypox virus (strain Zaire-96-I-16) A29L Protein, His Tag (Cat. No. A2L-M52H3) at 2μg/mL (100μL/well) can bind Monoclonal Anti-Monkeypox -A29L Antibody, Mouse IgG1 (8E8) (Cat. No. A2L-Y92) with a linear range of 0.02-50 ng/mL (QC tested).
Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded D. The cases are mostly in central and western Africa. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. A29L binds to cell surface heparin to promote fusion of viral membrane with host plasma membrane.