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Anti-SARS-CoV-2 Nucleocapsid Antibody-A5134, Human IgG1 (Trehalose free) (MALS verified)

抗体来源(Source)

Anti-SARS-CoV-2 Nucleocapsid Antibody-A5134, Human IgG1 is isolated from a Nucleocapsid protein infected Human and is recombinantly produced from human 293 cells (HEK293).

亚型(Isotype)

Human IgG1/Kappa

特异性(Specificity)

This product is a specific antibody specifically reacts with Nucleocapsid protein.

应用(Application)

ELISA

纯度(Purity)

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.2 μm filtered solution in PBS, pH7.4.

Contact us for customized product form or formulation.

运输(Shipping)

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储(Storage)

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. The product MUST be stored at -70°C or lower upon receipt;
  2. -70°C for 3 months under sterile conditions.
 

电泳(SDS-PAGE)

Nucleocapsid protein SDS-PAGE

Anti-SARS-CoV-2 Nucleocapsid Antibody-A5134, Human IgG1 on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS

Nucleocapsid protein SEC-MALS

The purity of Anti-SARS-CoV-2 Nucleocapsid Antibody-A5134, Human IgG1 (Cat. No. NUN-M507) is more than 90% and the molecular weight of this protein is around 140-160 kDa verified by SEC-MALS.

Report

 

活性(Bioactivity)-ELISA

Nucleocapsid protein ELISA

Immobilized SARS-CoV-2 Nucleocapsid protein, His Tag (Cat. No. NUN-C5227) at 1 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Nucleocapsid Antibody-A5134, Human IgG1 (Cat. No. NUN-M507) with a linear range of 0.1-1 ng/mL (QC tested).

Protocol

 

背景(Background)

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

 

前沿进展

 
 
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Nucleocapsid protein靶点信息
英文全称:Nucleocapsid proteins
中文全称:核壳蛋白
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:1详情
最高研发阶段:临床一期
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