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Human SLITRK6 Protein, Mouse IgG2a Fc Tag (MALS verified)

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分子别名(Synonym)

SLITRK6

表达区间及表达系统(Source)

Human SLITRK6, Mouse IgG2a Fc Tag (SL6-H5255) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Ser 608 (Accession # Q9H5Y7-1 ).

Predicted N-terminus: Ser 27

Request for sequence

蛋白结构(Molecular Characterization)

SLITRK6 Structure

This protein carries a mouse IgG2a Fc tag at the C-terminus.

The protein has a calculated MW of 91.7 kDa. The protein migrates as 100-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 0.1 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

SLITRK6 SDS-PAGE

Human SLITRK6, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS

SLITRK6 SEC-MALS

The purity of Human SLITRK6, Mouse IgG2a Fc Tag (Cat. No. SL6-H5255) is more than 90% and the molecular weight of this protein is around 196-239 kDa verified by SEC-MALS.

Report

 

活性(Bioactivity)-ELISA

SLITRK6 ELISA

Immobilized Human SLITRK6, Mouse IgG2a Fc Tag (Cat. No. SL6-H5255) at 2 μg/mL (100 μL/well) can bind Sirtratumab with a linear range of 0.5-16 ng/mL (QC tested).

Protocol

 

背景(Background)

SLIT and NTRK-like protein 6 (SLITRK6) belongs to the SLITRK family. SLITRK6 contains 11 LRR (leucine-rich) repeats, two LRRCT domains and two LRRNT domains. In adult brain, SLITRK6 is highly expressed in putamen and also is expressed in adult, fetal lung and fetal liver. SLITRK6 is also expressed at high levels in some brain tumors. Overexpression of SLITRK6 inhibites neurite outgrowth in cultured neurons.

 

前沿进展

 
 
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SLITRK6靶点信息
英文全称:SLIT and NTRK-like protein 6
中文全称:神经突触相关蛋白SLITRK6
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:1详情
最高研发阶段:临床一期
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