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Anti-Rabies virus glycoprotein G Antibody, Mouse IgG1 (523-11)

抗体来源(Source)

Anti-Rabies virus glycoprotein G Antibody, Mouse IgG1 (523-11) (RAG-M305) is a mouse monoclonal antibody recombinantly expressed from HEK293 cells.

亚型(Isotype)

Mouse IgG1/kappa

特异性(Specificity)

This antibody specifically binds to the glycoprotein of Rabies virus.

应用(Application)

ELISA

纯度(Purity)

>95% as determined by SDS-PAGE.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20 to -70°C for 12 months in lyophilized state from date of receipt;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Glycoprotein (RABV) SDS-PAGE

Anti-Rabies virus glycoprotein G Antibody, Mouse IgG1 (523-11) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

 

活性(Bioactivity)-ELISA

Glycoprotein (RABV) ELISA

Immobilized Rabies virus Glycoprotein, His Tag (Cat. No. RAG-V55H5) at 1 μg/mL (100 μL/well) can bind Mouse Glycoprotein G Antibody, Mouse IgG1 (523-11) (Cat. No. RAG-M305) with a linear range of 0.1-2 ng/mL (QC tested).

Protocol

 

背景(Background)

Rabies virus (RABV), scientific name Rabies lyssavirus, is a deadly neurotropic virus that causes rabies in humans and animals. Rabies virus has an extremely wide host range and its transmission most often occur through the saliva of animals. Without intervention prior to disease progression, rabies has the highest case fatality of any infectious disease. RABV contains a single-stranded negative-sense RNA genome that encodes five structural proteins: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G), and RNA-dependent RNA polymerase (L). Among these viral proteins, the RABV glycoprotein (RABV-G) is a pivotal player mediating virus entry and the major target of neutralizing antibodies, thus a key factor for vaccine and drug design.

 

前沿进展

 
 
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Glycoprotein (RABV)靶点信息
英文全称:Thrombospondin 1
中文全称:血小板1
种类:
上市药物数量:0详情
临床药物数量:1详情
最高研发阶段:临床一期
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