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 >  Protein>CD7 >CD7-H5253

Human CD7 Protein, Fc Tag (MALS verified)

分子别名(Synonym)

CD7,GP40,TP41,LEU-9,Tp40

表达区间及表达系统(Source)

Human CD7, Fc Tag (CD7-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Pro 180 (Accession # P09564-1 ).

Predicted N-terminus: Ala 26

Request for sequence

蛋白结构(Molecular Characterization)

CD7 Structure

This protein carries a human IgG1 Fc tag at the C-terminus.

The protein has a calculated MW of 42.9 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

CD7 SDS-PAGE

Human CD7, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS

CD7 SEC-MALS

The purity of Human CD7, Fc Tag (Cat. No. CD7-H5253) is more than 90% and the molecular weight of this protein is around 95-105 kDa verified by SEC-MALS.

Report

 

活性(Bioactivity)-ELISA

CD7 ELISA

Immobilized Human CD7, Fc Tag (Cat. No. CD7-H5253) at 1 μg/mL (100 μL/well) can bind Anti-CD7 antibody, Mouse IgG1 with a linear range of 0.2-2 ng/mL (QC tested).

Protocol

 

背景(Background)

T-cell antigen CD7 (CD7) is also known as GP40, LEU-9, TP41 and Tp40. CD7 is a protein that in humans is encoded by the CD7 gene, this gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. CD7 has been shown to interact with PIK3R1. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.

 

前沿进展

 
 
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CD7靶点信息
英文全称:T-cell antigen CD7
中文全称:T细胞抗原CD7
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:23详情
最高研发阶段:临床二期
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