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 > 【IL-17C】重组蛋白信息

IL-17C产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
ILC-H82E5
Human
Biotinylated Human IL-17C Protein, His,Avitag
ILC-H52H7
Human
Human IL-17C Protein, His Tag
 
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IL-17C Molecule Synonym Name

IL-17C,Cytokine CX2,IL17C

IL-17C 分子背景

Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL‑17C binds to IL‑17 RE with high affinity and to IL‑17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.

IL-17C 参考文献

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