搜索
 > 【PSCA】重组蛋白信息

PSCA信息

英文名称:Prostate stem cell antigen
中文名称:前列腺干细胞抗原
靶点别称:PSCA
上市药物数量:0
临床药物数量:4
最高研发阶段:临床二期

PSCA产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
PSA-H52H6
Human
Human PSCA Protein, His Tag
 
评论(0)
 

PSCA Molecule Synonym Name

PSCA,UNQ206,PRO232

PSCA 分子背景

The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

PSCA 参考文献

PSCA临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
124-iodine-labeled PSCA targeting minibody (ImaginAb) 临床一期 加州大学洛杉矶分校, ImaginAb 前列腺癌, 膀胱癌, 胰腺癌
Anti-PSCA-A11-antibody-I-124 (ImaginAb) 临床一期 加利福尼亚大学, ImaginAb 前列腺癌, 膀胱癌, 胰腺癌
Anti-PSCA monoclonal antibody (Agensys) AGS-1C4D4; AGS-PSCA; MK-4721 临床二期 Agensys 前列腺癌, 胰腺癌 详情
BPX-601 BPX-601 临床二期 Bellicum 胃癌, 前列腺癌, 食道腺癌, 膀胱癌, 胰腺癌 详情

消息提示

请输入您的联系方式,再点击提交!

确定