登录 | 注册    关注公众号  
微信公众号
搜索
 > 【Properdin】

Properdin信息

英文名称:Properdin
中文名称:备解素
靶点别称:Complement factor P,CFP
上市药物数量:0
临床药物数量:2
最高研发阶段:临床二期

Properdin产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
PRN-H52H3
Human
Human Properdin Protein, His Tag
PRN-M52H5
Mouse
Mouse Properdin Protein, His Tag
PRN-R52H6
Rhesus macaque
Rhesus macaque Properdin Protein, His Tag
ACRO质量管理体系
 
评论(0)
 

Properdin 分子别名

Properdin,Complement factor P,CFP,PFC

Properdin 分子背景

Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.

Properdin 前沿进展

Properdin临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Tarperprumig ALXN-1820 临床二期 Alexion Pharmaceuticals Inc 镰状细胞血症 详情
NM-5072 NM5072; NM-5072 临床一期 NovelMed Therapeutics Inc 阵发性血红蛋白尿症 详情

消息提示

请输入您的联系方式,再点击提交!

确定