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CX3CL1信息

英文名称:C-X3-C motif chemokine ligand 1
中文名称:C-X3-C基序趋化因子配体1
靶点别称:Neurotactin,SCYD1,CX3CL1,Small-inducible cytokine D1,FKN,C-X3-C motif chemokine 1,NTT,CX3C membrane-anchored chemokine
上市药物数量:0
临床药物数量:1
最高研发阶段:临床二期

CX3CL1产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
CX1-H8221
Human
Biotinylated Human CX3CL1, ultra sensitivity (primary amine labeling)
CX1-H5221
Human
Human CX3CL1 / Fractalkine Protein

CX3CL1 分子别名

CX3CL1,Fractalkine

CX3CL1 分子背景

Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin. Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells. It has also been found to be essential for microglial cell migration. CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.

CX3CL1 参考文献

CX3CL1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Quetmolimab E-6011; KANAB-001; E6011; KANAb001 临床二期 卫材 类风湿性关节炎, 克罗恩氏病 详情

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