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LRRC32产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
LR2-H5256
Human
Human LRRC32 / GARP / Garpin / D11S833E Protein, Fc Tag
 
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LRRC32 分子别名

GARP,Garpin,D11S833E

LRRC32 分子背景

Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naïve T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation.

LRRC32 参考文献

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