Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5), also known as CD85c and LIR-8, belongs to the leukocyte immunoglobulin-like receptor (LIR) family of transmembrane glycoproteins that negatively regulate immune cell activation. Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response.
- Liu T., et al., 2006, J. Proteome Res., 4 (6): 2070-2080.
- Thomas, R. et al., 2010, Clin. Rev. Allergy Immunol., 38: 159-162.
- Zheng, J. et al., 2012, Nature, 485: 656-660.