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 > 【Glycoprotein G / G】

Glycoprotein G / G信息

英文名称:Thrombospondin 1
中文名称:血小板1
靶点别称:TSP,Glycoprotein G,THBS1,Thrombospondin-1p180,TSP1,Thrombospondin-P50,Thrombospondin-1,THBS-1,TSP-1,THBS,Thrombospondin 1
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

Glycoprotein G / G产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
RSG-V5221
HRSV
HRSV (A) Glycoprotein G Protein, His Tag
ACRO质量管理体系
 
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Glycoprotein G / G分子别名

Glycoprotein G,G,mG,Attachment glycoprotein G,Membrane-bound glycoprotein

Glycoprotein G / G分子背景

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. Human respiratory syncytial virus A (strain Long) major surface glycoprotein G (RSV-G), a member of the pneumoviruses glycoprotein G family, is also known as attachment glycoprotein G and membrane-bound glycoprotein (mG), which contains a linear heparin binding domain essential for virus attachment to the host. Concretely speaking, RSV-G can attache the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Furthermore, RSV-G can also interact with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, RSV-G lacks both neuraminidase and hemagglutinating activities.

Glycoprotein G / G临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
VT-1021 VT-1021 临床一期 Vigeo Therapeutics Inc 实体瘤 详情

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