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 > 【LIF】重组蛋白信息

LIF产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
LIF-H521b
Human
ActiveMax® Human LIF Protein, Tag Free
LIF-M5227
Mouse
Mouse LIF Protein, His Tag
LIF-H82E2
Human
Biotinylated Human LIF Protein, His,Avitag
 
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LIF 分子别名

LIF,CDF,DIA,HILDA,MLPLI

LIF 分子背景

Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.

LIF 参考文献

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