搜索
 > 【TFPI-2】重组蛋白信息

TFPI-2产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
TF2-H5227
Human
Human TFPI-2 Protein, His Tag
 
评论(0)
 

TFPI-2 分子别名

TFPI2,PP5,REF1

TFPI-2 分子背景

Tissue Factor Pathway Inhibitor 2 (TFPI­2) is also known as placental protein 5 (PP5) and retinal pigment epithelial cell factor 1 (REF­1), is a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). TFPI2 is highly abundant in the full-term placenta and widely expressed in umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy. TFPI­2 may play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa and has no effect on thrombin. Reduced synthesis of TFPI-2 has been related to numerous pathophysiological processes such as inflammation, angiogenesis, atherosclerosis, retinal degeneration and tumor growth / metastasis.

TFPI-2 参考文献

消息提示

请输入您的联系方式,再点击提交!

确定