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TDGF1信息

英文名称:Teratocarcinoma-derived growth factor 1
中文名称:畸胎瘤衍生生长因子-1
靶点别称:CRGF,CRIPTO,Cripto-1 growth factor,TDGF1,Epidermal growth factor-like cripto protein CR1
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

TDGF1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CRO-H5253
Human
Human Cripto /TDGF1 Protein,C-Fc Tag,HEK293 expressed
 
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TDGF1 分子别名

TDGF1,CRGF,CRIPTO

TDGF1 分子背景

Teratocarcinoma-derived growth factor 1 (TDGF1) is also known as Cripto-1 growth factor (CRGF), Epidermal growth factor-like cripto protein CR1, CRIPTO, is a cell membrane which contains one EGF-like domain. TDGF1 is preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. TDGF1 interacts with the activin type-1 receptor ACVR1B. TDGF1 could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

TDGF1 参考文献

TDGF1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
BIIB-015 BIIB-015 临床一期 百健 实体瘤 详情

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