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Stathmin 1产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
ST1-H5149
Human
Human Stathmin 1 / STMN1 Protein, His Tag
 
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Stathmin 1 分子别名

STMN1,Stathmin,C1orf215,LAP18,OP18

Stathmin 1 分子背景

Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.

Stathmin 1 参考文献

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