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PSME3产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
PS3-H5142
Human
Human PSME3 / PA28g Protein, His Tag
 
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PSME3 分子别名

PSME3,PA28gamma,REG-gamma

PSME3 分子背景

Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation.

PSME3 参考文献

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