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 > 【Osteoactivin】重组蛋白信息

Osteoactivin产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
GPB-H5229
Human
Human Osteoactivin / GPNMB Protein, His Tag

Osteoactivin 分子别名

GPNMB,HGFIN,NMB,Osteoactivin

Osteoactivin 分子背景

Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.

Osteoactivin 参考文献

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