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 > 【MBL】重组蛋白信息

MBL信息

英文名称:Mannose-binding protein C
中文名称:甘露糖结合蛋白C
靶点别称:Collectin-1,Mannose-binding lectin,MBL,MBP1,COLEC1 ,MBL2,Mannan-binding protein,Mannose-binding protein C,MBP-C
上市药物数量:0
临床药物数量:1
最高研发阶段:临床二期

MBL产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
MBL-H5220
Human
Recombinant Human Mannose-binding lectin / MBL Protein

MBL 分子别名

MBL,MBL2,MBP1,MBP-C,Collectin-1,COLEC1,HSMBPC,MBL2D,MBPD

MBL 分子背景

Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.

MBL 参考文献

MBL临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Recombinant human mannose-binding lectin (NatImmune/Enzon) 临床二期 NatImmune A/S, Enzon Pharmaceuticals 感染类疾病 详情

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