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LTBR信息

英文名称:Tumor necrosis factor receptor superfamily member 3
中文名称:肿瘤坏死因子受体超家族成员3
靶点别称:Lymphotoxin-beta receptor,TNFRSF3,Tumor necrosis factor receptor superfamily member 3,Tumor necrosis factor receptor 2-related protein,TNFR-III,TNFR3,Tumor necrosis factor C receptor,Tumor necrosis factor receptor type III,D12S370 ,TNF-RIII,TNFCR,LTBR
上市药物数量:0
临床药物数量:1
最高研发阶段:临床二期

LTBR产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
LTR-H5251
Human
Human LTBR /TNFRSF3 Protein,C-Fc Tag

LTBR 分子别名

LTBR,D12S370,TNFCR,TNFR3,TNFRSF3,TNFRIII

LTBR 分子背景

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.

LTBR 参考文献

LTBR临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Baminercept BG-9924,BG 9924 临床二期 百健, 国家过敏和传染病研究所 干燥综合征 详情

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