搜索
 > 【LRP-10】重组蛋白信息

LRP-10产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
LR0-H5259
Human
Human Low-density lipoprotein receptor-related protein 10 (LRP10) Protein,C-Fc Tag

LRP-10 分子别名

LRP10,MSTP087,SP220,UNQ389,PRO724

LRP-10 分子背景

Low-density lipoprotein receptor-related protein 10 (LRP10), a member of the LDLR family, is a single-pass type I membrane protein, which contains two CUB domains and four LDL-receptor class A domains. As a probable receptor, LRP10 is involved in the internalization of lipophilic molecules or signal transduction. LRP10 may be involved in the uptake of lipoprotein APOE in liver. Furthermore, Deletion of the extracellular domain of LRP10 negated its inhibitory effect. It sugested that LRP10 may interfere with the formation of the beta-catenin/TCF complex and its binding to target DNA in the nucleus, and that the extracellular domain of LRP10 is critical for inhibition of the canonical Wnt/beta-catenin signaling pathway. LRP10 has been improved to play a significant role in the brain physiology other than lipoprotein metabolism.

LRP-10 参考文献

消息提示

请输入您的联系方式,再点击提交!

确定