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KIR2DL3信息

英文名称:Killer cell immunoglobulin-like receptor 2DL3
中文名称:杀伤细胞免疫球蛋白样受体2DL3
靶点别称:NKAT2b,p58 natural killer cell receptor clone CL-6,Killer inhibitory receptor cl 2-3,NKAT2a,MHC class I NK cell receptor,NKAT-2,KIRCL23,Natural killer-associated transcript 2,p58 NK receptor CL-6,KIR2DL3,p58.2 MHC class-I-specific NK receptor,CD158B2 ,KIR
上市药物数量:0
临床药物数量:1
最高研发阶段:临床二期

KIR2DL3产品列表

产品库
物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
KI3-H5226
Human
Human KIR2DL3 / CD158b2 Protein, His Tag
KI3-H5257
Human
Human KIR2DL3 /CD158B2 Protein,C-Fc Tag
 
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KIR2DL3 分子别名

KIR2DL3,CD158B2,KIRCL23,NKAT2,KIR-023GB,NKAT2a,NKAT2b,NKAT-2,CD158 B2,GL183,KIR-023GB,KIR-K7b,KIR-K7c,KIRCL23,NKAT,p58

KIR2DL3 分子背景

Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) is also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, which is a single-pass type I membrane protein and belongs to the immunoglobulin superfamily.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 can inhibit the activity of NK cells thus preventing cell lysis.

KIR2DL3 参考文献

KIR2DL3临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Lirilumab BMS-986015; IPH-21; IPH-2101; IPH-2102; NN-1975 临床二期 诺和诺德, 百时美施贵宝, 小野制药, Innate 骨髓增生异常综合征, 慢性淋巴细胞白血病, 头颈癌 详情

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