搜索
 > 【IL-2 R alpha】重组蛋白信息

IL-2 R alpha产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
ILA-H52H9
Human
Human IL-2 R alpha / CD25 Protein, His Tag
ILA-H5251
Human
Human IL2RA /CD25 Protein,C-Fc Tag
ILA-H82E6
Human
Biotinylated Human IL-2 R alpha / CD25 Protein, His Tag, Avi Tag
ILA-M52H9
Mouse
Mouse IL-2 R alpha / CD25 Protein, His Tag

IL-2 R alpha 分子别名

IL2RA,CD25,p55,IL2-RA,IL-2-RA

IL-2 R alpha 分子背景

Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.

IL-2 R alpha 参考文献

消息提示

请输入您的联系方式,再点击提交!

确定