搜索
 > 【IGFBP-4】重组蛋白信息

IGFBP-4产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
IG4-H52E4
Human
Human IGFBP-4 Protein

IGFBP-4 分子别名

IGFBP4,IBP-4

IGFBP-4 分子背景

Insulin-like growth factor-binding protein 4 (IGFBP-4) is also known as IGF-binding protein 4, which contains an IGFBP domain and a thyroglobulin type-I domain. IGFBP-4 binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. IGFBP-4 is a unique protein and it consistently inhibits several cancer cells in vivo and in vitro. Its inhibitory action has been shown in vivo in prostate and colon. IGFBP-4 is secreted by all colon cancer cells.

IGFBP-4 参考文献

消息提示

请输入您的联系方式,再点击提交!

确定