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GAPDH信息

英文名称:Glyceraldehyde-3-phosphate dehydrogenase liver
中文名称:肝甘油醛-3-磷酸脱氢酶
靶点别称:GAPDH,Peptidyl-cysteine S-nitrosylase GAPDH,GAPD,OK/SW-cl.12,Glyceraldehyde-3-phosphate dehydrogenase
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

GAPDH产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
GAH-H5145
Human
Recombinant Human GAPDH / G3PDH Protein

GAPDH 分子别名

GAPDH,GAPD,CDABP0047,OK/SW-cl.12

GAPDH 分子背景

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is also known as Peptidyl-cysteine S-nitrosylase GAPDH, which is an enzyme that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. GAPDH has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. GAPDH can participate in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Also, GAPDH can modulate the organization and assembly of the cytoskeleton. Furthermore, GAPDH is a component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.

GAPDH 参考文献

GAPDH临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Omigapil CGP-3466; SNT-317; TCH-346; CGP-3466 maleate; CGP-3466B,CGP3466,SNT317,TCH346 临床一期 Santhera Pharmaceuticals 先天性肌营养不良症 详情

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