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 > 【Frizzled-4】重组蛋白信息

Frizzled-4产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
FZ4-H5250
Human
Recombinant Human Frizzled-4 / FZD4 / CD344 Protein
 
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Frizzled-4 分子别名

FZD4,Frizzled-4,CD344,Fz-4,hFz4,FzE4

Frizzled-4 分子背景

Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).

Frizzled-4 参考文献

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