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Frizzled-4信息

英文名称:Frizzled-4
中文名称:卷曲蛋白-4
靶点别称:hFz4,FzE4,CD344,Frizzled 4, Seven Transmembrane Spanning Receptor,Fz-4,Frizzled Family Receptor 4,EVR1,Frizzled (Drosophila) Homolog 4,Frizzled Homolog 4 (Drosophila),Exudative Vitreoretinopathy 1,WNT Receptor Frizzled-4,Frizzled Homolog 4,CD344 Antigen,FZD4S,FEVR,GPCR,Fz4
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

Frizzled-4产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
FZ4-H5250
Human
Human FZD4 /Frizzled-4 /CD344 Protein, with C-Fc Tag
ACRO质量管理体系
 
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Frizzled-4 分子别名

FZD4,Frizzled-4,CD344,Fz-4,hFz4,FzE4

Frizzled-4 分子背景

Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).

Frizzled-4 前沿进展

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