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 > 【Frizzled-2】重组蛋白信息

Frizzled-2产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
FZ2-H5251
Human
Human FZD2 /Frizzled-2 Protein, with C-Fc Tag
FZ2-H5255
Human
Human Frizzled-2 / FZD2 (24-190) Protein, Fc Tag

Frizzled-2 分子别名

FZD2,Frizzled-2,Fz-2,hFz2,FzE2

Frizzled-2 分子背景

Frizzled-2 (FZD2) is also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD2 contains one FZ (frizzled) domain. FZD2 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. The Lys-Thr-X-X-X-Trp motif of FZD2 interacts with the PDZ doman of Dvl (Disheveled) family members and is involved in the activation of the Wnt/beta-catenin signaling pathway.

Frizzled-2 参考文献

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