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DPPIV产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
DP4-H5266
Human
Human-DPPIV-DPP4-CD26-Protein-Fc-Tag
DP4-H5211
Human
Human DPPIV /DPP4 /CD26 Protein,Tag Free
DP4-H5221
Human
Human DPPIV / CD26 Protein, His Tag
 
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DPPIV 分子别名

DPP4,ADABP,ADCP2,CD26,DPPIV,TP103

DPPIV 分子背景

Dipeptidyl peptidase-IV (DPPIV) is also known as adenosine deaminase complexing protein 2, DPPIV or CD26 is antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. The substrates of DPPIV are proline (or alanine)-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1. DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others.[4] DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity. The significance of this interaction has yet to be established.

DPPIV 参考文献

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